Oligoasthenotratosospermia. Male infertility
Conditions
Interventions
Intervention 1: Intervention group: group of Zayesh Majoon(Twice a day, 8 grams each time), Royal Jelly capsule and Safof hefz capsule (made by BooaliDaroo company) Twice a day for a 90-day period. In
Sponsors
Iranian academic center for education culture and research
Eligibility
Sex/Gender
Male
Age
20 Years to 50 Years
Inclusion criteria
Inclusion criteria: Patients with oligo asthenotratospermia(Total sperm count is 15 or less than 15 million per milliliter.The percentage of normal morphology or appearance is less than 4.Sperm motility is less than 40%. The patient's spouse is fertile. Have a history of infertility for at least one year.
Exclusion criteria
Exclusion criteria: History of receiving chemotherapy drugs, corticosteroids, anticoagulants, testosterone, anti-androgens two months before the start of the study Genital infections, anatomical abnormalities, chromosomal abnormalities, history of genital surgery (varicocele, ...) Alcohol or drug use Patients with Ejaculation disorder Systemic diseases (malignancy, thyroid disease, liver and gallbladder) Cr>1.5 Sgot>80 Sgpt>80 Hb<10
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sperm count. Timepoint: Before the intervention and 3 months after the intervention. Method of measurement: optical microscope.;Sperm motility. Timepoint: Before the intervention and 3 months after the intervention. Method of measurement: optical microscope.;Sperm morphology. Timepoint: Before the intervention and 3 months after the intervention. Method of measurement: staining.;Sperm DNA fragmentation. Timepoint: Before the intervention and 3 months after the intervention. Method of measurement: optical microscope.;Protamine deficiency. Timepoint: Before the intervention and 3 months after the intervention. Method of measurement: Fluorescent microscope. | — |
Secondary
| Measure | Time frame |
|---|---|
| Follicle-stimulating hormone,Luteinizing Hormone,Testosterone. Timepoint: Before the intervention and 3 months after the intervention. Method of measurement: kit.;Malondialdehyde. Timepoint: Before the intervention and 3 months after the intervention. Method of measurement: ELISA Kit.;Total antioxidant capacity. Timepoint: Before the intervention and 3 months after the intervention. Method of measurement: ELISA Kit.;Erectile quality. Timepoint: Before the intervention and 3 months after the intervention. Method of measurement: International Index of Erectile Function Questionnaire (IIEF).;Quality of sexual life. Timepoint: Before the intervention and 3 months after the intervention. Method of measurement: Sexual Quality of Life Questionnaire (SQOL). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactLeila Naserpour
Iranian academic center for education culture and research
Outcome results
None listed