Acute liver failure. Fibrosis and cirrhosis of liver
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Recipients with acute liver failue and MELD score> 20 requiring urgent liver transplant Recipients should have Negetive PCR test/ NO COVID-19 signs and symptoms/ NO lung involvement in HRCT Deceased donors with positive PCR tests or COVID-19 lung involvement in HRCT
Exclusion criteria
Exclusion criteria: Recipients with clinical presentation of COVID-19 OR positive PCR test OR lung involvement in HRCT Deceased donors due to respiratory failure
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Description of early outcomes of liver transplant from COVID-19 positive deceased donors. Timepoint: 30 days within operation. Method of measurement: Clinical assessments/ liver functional tests.;Evaluation of transmission of COVID-19. Timepoint: 24 hours, day 7 and 14 postoperatively. Method of measurement: Clinical manifestations, PCR test, lung HRCT. | — |
Secondary
| Measure | Time frame |
|---|---|
| Long term outcomes of liver transplant from COVID-19 positive deceased donors. Timepoint: 6 months and 1 year postoperatively. Method of measurement: Clinical follow ups and liver function tests. | — |
Countries
Iran (Islamic Republic of)
Contacts
Mashhad University of Medical Sciences