COVID-19. COVID-19, virus identified
Conditions
Interventions
Intervention 1: Standard treatment + sublingual drop containing squalene, 15 drops for the first day of admission and then 10 drops a day for 4 days. Intervention 2: standard treatment: Since the effe
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patient with definite COVID-19 confirmed by molecular or imaging methods in which the oxygen saturation level is less than 93% (SPO2 <93%) and requires respiratory support including oxygen therapy. Patient with definite COVID-19 confirmed by molecular or imaging methods with hypotension (systolic pressure less than 90) Patient with definite COVID-19 confirmed by molecular or imaging methods with Persistence of dehydration and oral intolerance after outpatient supportive care Patient with definite COVID-19 confirmed by molecular or imaging methods who are considered as high risk patient regardless of the clinical symptoms based on the underlying disease, clinical condition, and paraclinical findings. (Uncontrolled high blood pressure, uncontrolled diabetes, obesity, etc.)
Exclusion criteria
Exclusion criteria: History of myocardial ischemia, heart failure and advanced COPD Dissatisfaction of the patient or the patient's companion Any mental disability that prevents effective communication Existence of any physical disability that prevents one from performing daily activities independently. (Physical disability leads to disability before COVID-19 infection) History of alcohol or drug abuse Possibility of pregnancy and lactation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fever. Timepoint: Daily for 7days. Method of measurement: thermometer.;SPO2. Timepoint: daily for 7 days if hospitalization continued. Method of measurement: Pulse oxymeter.;Respiratory rate. Timepoint: daily for 7 days. Method of measurement: respiration in one minute.;Food tolerance. Timepoint: daily for 7 days. Method of measurement: physician judgment. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMahmoud Ebrahimi
Mashhad University of Medical Sciences
Outcome results
None listed