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Estrogen in non allergic rhinitis

Effectiveness of topical esterogen on non allergic rhinitis in post menopausal women

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200926048841N2
Enrollment
25
Registered
2022-05-16
Start date
2022-05-22
Completion date
Unknown
Last updated
2022-05-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vasomotor rhinitis. Vasomotor rhinitis

Interventions

Intervention 1: Intervention group: Take intra nasal conjugated estrogen ointment daily(50 mg containing 300 micrograms of estrogen) for 3 months. Intervention 2: Control group: They were treated with

Sponsors

Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Menopausal women 12 months after their last menstrual bleeding Symptoms of nasal congestion (feeling of fullness in the nose, feeling of discomfort and heaviness in the nose - feeling of reduced airflow in the nose, loss of smell or mouth breathing)

Exclusion criteria

Exclusion criteria: Use of drugs affecting the nasal airway and nasal mucosa (systemic and local) Systemic underlying diseases Previous history of rhinoplasty and sinus surgery Obstructive symptoms before menopause Presence of known sinonasal diseases, including pulpitis, chronic sinusitis, sinonasal tumors (both benign and malignant) Smoking and inhaled drugs Occupational exposure to chemical stimulants and its history Patients w?ho did not have the proper cooperation for rhinomanometry, endoscopy and the use of drugs and follow-up Patients for whom estrogen use is contraindicated

Design outcomes

Primary

MeasureTime frame
Effect of estrogen on rhinitis. Timepoint: Three months after treatment. Method of measurement: Rhinomanometry.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMahboobe Asadi

Shahid Beheshti University of Medical Sciences

mahboobeh_farvardin@yahoo.com+98 21 2303 1317

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026