Effect of Persian medicine product on the recovery and relapse of bacterial vaginosis

Comparison of the effectiveness of traditional medicine product and metronidazole vaginal gel in the treatment and prevention of recurrence in patients with bacterial vaginosis

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200926048840N1

Enrollment

Registered

2021-09-29

Start date

2021-10-12

Completion date

Unknown

Last updated

2021-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bacterial vaginosis. N76.0

Interventions

Intervention 1: Intervention group: 10% vaginal gel prepared from aqueous extract of rhubarb root and oral capsule containing 200 mg of aqueous extract of rhubarb root will be used for a week to treat

Eligibility

Sex/Gender

Female

Age

18 Years to 55 Years

Inclusion criteria

Inclusion criteria: Married women 18 -50 years old Positive at least 3 out of 4 Amsel criteria

Exclusion criteria

Exclusion criteria: Pregnancy Lactation Menopause Vaginal bleeding Use of antibiotics in the last 4 weeks Known chronic diseases Using oral contraceptives to prevent pregnancy Smoking and Consuming alcohol Using Coumarin anticoagulants Multiple sexual partners Diarrhea

Design outcomes

Primary

Measure	Time frame
Cure (Elimination of all Amsel criteria or remaining only one criterion and according to the agent scoring system, a score of 1 to 3 or 4 to 6 without key cells). Timepoint: 10 days after the start of treatment and 30 days after the end of treatment. Method of measurement: Amsel and Najnat criteria.	—

Secondary

Measure	Time frame
Vaginal discharge. Timepoint: 10 days after the start of treatment and 30 days after the end of treatment. Method of measurement: observation.;Vaginal acidity. Timepoint: 10 days after the start of treatment and 30 days after the end of treatment. Method of measurement: Ph strip.;Whiff test. Timepoint: 10 days after the start of treatment and 30 days after the end of treatment. Method of measurement: Koh 10% solution.;Clue cells. Timepoint: 10 days after the start of treatment and 30 days after the end of treatment. Method of measurement: Evaluation of clue cells in the wet lam.;Nagnet score. Timepoint: 10 days after the start of treatment and 30 days after the end of treatment. Method of measurement: Evaluation of stained slide.	—

Measure

Time frame

Vaginal discharge. Timepoint: 10 days after the start of treatment and 30 days after the end of treatment. Method of measurement: observation.;Vaginal acidity. Timepoint: 10 days after the start of treatment and 30 days after the end of treatment. Method of measurement: Ph strip.;Whiff test. Timepoint: 10 days after the start of treatment and 30 days after the end of treatment. Method of measurement: Koh 10% solution.;Clue cells. Timepoint: 10 days after the start of treatment and 30 days after the end of treatment. Method of measurement: Evaluation of clue cells in the wet lam.;Nagnet score. Timepoint: 10 days after the start of treatment and 30 days after the end of treatment. Method of measurement: Evaluation of stained slide.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactSedigheh Moosaei

Mashhad University of Medical Sciences

Mousaeis941@mums.ac.ir+98 51 3884 8931

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026