Endometriosis. Endometriosis of ovary
Conditions
Interventions
Intervention 1: Intervention group: Silibum Marianum 140 mg twice daily and 30 mg medroxyprogesterone for six months. Intervention 2: Control group: Placebo (starch) tablets twice daily and medroxypr
Sponsors
Shiraz University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: Endometriosis recorded by transvaginal ultrasound or transrectal ultrasound by a gynecologist No history of endometriosis surgery Without any chronic inflammatory disease and chronic medical conditions such as cancer, diabetes, cardiovascular disease and rheumatic disease Age less than 45 years old The patient is without surgical indication
Exclusion criteria
Exclusion criteria: Breast Cancer probability of side effects such as severe nausea, vomiting, diarrhea or gastrointestinal symptoms Previous endometriosis surgery Cervical or ovarian cancer Uterine fibroid
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| AMH level. Timepoint: Six months after starting the medication. Method of measurement: Hormone kits (Diazist).;Endometrioma size. Timepoint: At the beginning of the study and 6 months later. Method of measurement: Transvaginal or transrectal ultrasonography. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr.Elham Askari
Shiraz University of Medical Sciences
Outcome results
None listed