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Investigating the effect of adding memantine to current therapies on the symptoms of post-traumatic stress disorder

Investigating the effect of adding memantine to current therapies on the symptoms of post-traumatic stress disorder

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200923048816N1
Enrollment
30
Registered
2020-10-13
Start date
2020-09-11
Completion date
Unknown
Last updated
2020-11-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-traumatic stress disorder. Post-traumatic stress disorder (PTSD)

Interventions

Intervention 1: Intervention group: Current treatment with memantine Patients in the first group or intervention group, in addition to the current treatment, are t

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
19 Years to 65 Years

Inclusion criteria

Inclusion criteria: Male and female patients with an age range of 19 to 65 years A case of battlefield PTSD diagnosed at least 12 months in advance according to DSM 5 criteria

Exclusion criteria

Exclusion criteria: Patients with a history of dementia, schizophrenia, bipolar disorder, anxiety disorders, traumatic brain injury, and seizures according to DSM 5 criteria Patients with a history of alcohol and psychotropic drug use in the last month or the presence of addiction in the patient's history Patients need treatment with drugs that affect the glutamatergic system such as amantadine, dexamethasone or carbonic anhydrase inhibitors

Design outcomes

Primary

MeasureTime frame
Symptoms of post-traumatic stress disorder. Timepoint: At the beginning of the study, the eighth week and the sixteenth week. Method of measurement: Clinical Administered PTSD Scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemeh Fozveh

Esfahan University of Medical Sciences

drfozveh.f@gmail.com+98 31 3786 1563

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026