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The effect of synbiotic on inflammatory markers and clinical manifestations in patients with C0VID-19

Evaluation of the complementary effect of synbiotic adjuvant on inflammatory markers and clinical manifestations in patients with COVID-19

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200923048815N1
Enrollment
80
Registered
2020-10-15
Start date
2020-10-22
Completion date
Unknown
Last updated
2020-11-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronavirus infection. Coronavirus infection, unspecified

Interventions

Intervention 1: Intervention group: Patients in this group use Lactocar brand Synbiotic in the form of 250 capsules containing 7 probiotic strains. Two capsules are consumed every day after lunch for

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Age 18-70 years old Basic literacy Writing ability and healthy memory Mental conditions for continuing to attend the study and completing the consent form

Exclusion criteria

Exclusion criteria: Simultaneous participation in other clinical trial studies Having other acute and serious diseases Regular and periodic consumption of special dietary supplements or special diets Taking other probiotic supplements Receive corticosteroids in full dose People with pancreatitis, sepsis, dialysis, central venous and chronic diarrhea People waiting for abdominal surgery People with acute immune deficiencies such as AIDS People with short bowel syndrome or are at risk for mesenteric ischemia Pregnant women and mothers who are breastfeeding.

Design outcomes

Primary

MeasureTime frame
Inflammatory markers. Timepoint: Before and 8 weeks after start of intervention. Method of measurement: Biochemical analysis.

Secondary

MeasureTime frame
Clinical symptoms. Timepoint: Before intervention and 8 weeks after intervention. Method of measurement: Comment by physician.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMajid Aghadavood Marnani

Esfahan University of Medical Sciences

Majid.aghadavood@gmail.com+98 31 3620 2020

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026