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Assessment of the effect of local application of Aloe Vera gel in treatment of gum inflammation in diabetic patients

Assessment of the effect of local application of Aloe Vera gel as a non-surgical adjunctive treatment in type 2 diabetic patients with chronic periodontitis referring to Gorgan dental school

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200919048760N1
Enrollment
44
Registered
2020-09-23
Start date
2020-09-26
Completion date
Unknown
Last updated
2020-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Type 2 diabetic patients with chronic periodontitis. Condition 2: Type 2 diabetic patients with chronic periodontitis.

Interventions

Intervention group: The procedure will be in the form of a split mouth in such a way that randomly with a pre-prepared randomization list, half of one patient&#39
s jaw is treated only with scaling and root planing (control group) and half The other jaw will be treated with scaling and root planing with local application of aloe vera gel (test group). In the co
s gums without applying any force so that some of the gel leaks out of the gingival margin. One week after the first stage of treatment, the patient will be placed the gel again..

Sponsors

Gorgan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Type 2 diabetic patients Being over 18 years old Having at least 20 teeth in the mouth Having at least one area with an pocket depth of 4 mm and more and with a loss of clinical attachment of 3 mm and more in four or more teeth in at least two quadrants The need for availability during the research process Having conscious satisfaction

Exclusion criteria

Exclusion criteria: Receive systemic or topical antibiotic therapy in the last 3 months Consumption of antioxidants including vitamin C or E in the last 3 months Receive scaling and root planing treatment in the last 6 months History of any periodontal treatment, both surgical and non-surgical, during the last 6 months Patients undergoing orthodontic treatment Patients with uncontrolled diabetes (HbA1C> 7) Tobacco consumption alcohol consumption Patients with aggressive periodontitis Pregnancy and lactation

Design outcomes

Primary

MeasureTime frame
Probing pocket depth (PPD) in millimeters Clinical attachment level (CAL) in millimeters Gingival index (GI) in terms of graded determination plaque index (PI) in percentage. Timepoint: The time of measurement of variables is at the beginning of the study (before the intervention), 1 month and 3 months after treatment. Method of measurement: probing pocket depth (PPD) in millimeters by Williams periodontal probe Clinical attachment level (CAL) in millimeters by Williams periodontal probe. Gingival index (GI) according to the assigned grading: GI0 (normal): Pink gums Normal, non-inflammatory GI1 (mild): Slightly discolored gums, Negative BOP GI2 (moderate): Red, shiny, swollen gums, Positive BOP GI3 (severe): Gums red, swollen, with spontaneous sores and bleeding / Examination with periodontal probe . Plaque index (PI): How to measure PI: (Number of painted surfaces * 100) / (Number of teeth * 4) Percentage: Optimal: 0-30 Medium: 31-50 Unfavorable: 51-100.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactIman Zarei Sani

Gorgan University of Medical Sciences

zarei.i@goums.ac.ir+98 17 3262 7824

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026