Investigating the hemostatic effect of a surgical hemostat sponge

Investigating the hemostatic effect of a surgical hemostat sponge containing aloevera nanoparticles after extraction of the mandible first and second molars

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200919048756N8

Enrollment

Registered

2024-05-16

Start date

2024-05-30

Completion date

Unknown

Last updated

2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Extraction of the first and second mandibular teeth. Alveolitis of jaws

Interventions

Intervention 1: Intervention group: One of the two first or second mandibular of patients in which the production geltamp (a sponge made of gelatin without any drug) will be placed. How to use

In each patient, after extracting the tooth, a production geltamp will be placed in the extracted tooth cavity. Duration of use: It will remain in the place for at least 4 days and after that, it can

In each patient, after extracting the tooth, a commercial geltamp will be placed in the extracted tooth cavity. Duration of use: It will remain in the place for at least 4 days and after that, it can

Eligibility

Sex/Gender

All

Age

20 Years to 45 Years

Inclusion criteria

Inclusion criteria: Need for extraction of two mandibular first molars Age between 20-45 years No corticosteroids and antibiotics using in the last month No coagulation disorders No acute or uncontrolled infection at the dental surgery site No malignancy at the dental surgery site No site exposure Radiation surgery No contraceptives using at last month No smoking No hypertension, diabetes, thyroid disorders and blood diseases

Exclusion criteria

Exclusion criteria: People taking anticoagulants Not signing the consent form Having a systemic disease Patients whose teeth do not come out normally and need surgery and sectioning

Design outcomes

Primary

Measure	Time frame
Blood clotting. Timepoint: The amount of bleeding will be recorded after the anesthesia is gone (within 1-4 hours after tooth extraction) and the amount of uncontrollable bleeding after 4 hours will be considered as active bleeding. Method of measurement: In the study groups, sterile gas is changed every 15 minutes to completely stop the bleeding. The difference in weight of sterile gauze at the beginning and after blood absorption will indicate the amount of blood absorption of each sterile gauze. The number of sterile gauzes consumed and the total weight of sterile blood gauzes absorbed in each group (test and control) will be compared.	—

Measure

Time frame

Blood clotting. Timepoint: The amount of bleeding will be recorded after the anesthesia is gone (within 1-4 hours after tooth extraction) and the amount of uncontrollable bleeding after 4 hours will be considered as active bleeding. Method of measurement: In the study groups, sterile gas is changed every 15 minutes to completely stop the bleeding. The difference in weight of sterile gauze at the beginning and after blood absorption will indicate the amount of blood absorption of each sterile gauze. The number of sterile gauzes consumed and the total weight of sterile blood gauzes absorbed in each group (test and control) will be compared.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Ali Ghavimi

Tabriz University of Medical Sciences

m_ghavimi@yahoo.com+98 41 3335 3161

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026