The effect of 0.25% sodium hypochlorite mouthwash on gingivitis

Comparison of the effect of hypochlorite sodium 0.25% and chlorhexidine 0.2% mouthwash on periodontal indices in treatment of patients with chronic gingivitis : A control clinical trial study

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200916048739N1

Enrollment

Registered

2020-10-08

Start date

2020-10-06

Completion date

Unknown

Last updated

2020-11-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gingivitis. Chronic gingivitis

Interventions

Intervention 1: Intervention group: Patients in this group use sodium hypochlorite mouthwash with NACLO chemical composition and concentration of 0.25% (15 mililitr), twice a day for two weeks after b

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with Generalized marginal and papillary gingivitis

Exclusion criteria

Exclusion criteria: Patients with periodontitis Diabetic patients , Severe systemic cardiac patients Patients who have received antibiotics in the last 6 months Patients with necrotizing periodontitis Systemic diseases that cause generalized gingivitis Patients with a positive history of HIV, AIDS Patients with tobacco usage in smoked or smokeless form Immunosuppressive drug therapy or use of medications affecting gingival enlargement

Design outcomes

Primary

Measure	Time frame
Bleeding On Probing Index (BOP). Timepoint: At the beginning of the study and 14 days after starting mouthwash. Method of measurement: Using periodontal probe.;Modified Gingival Index (MGI). Timepoint: At the beginning of the study and 14 days after starting mouthwash. Method of measurement: Visual observation.;Plaque Index (PI). Timepoint: At the beginning of the study and 14 days after starting mouthwash. Method of measurement: Using periodontal probe, Loe and Silness method.	—

Measure

Time frame

Bleeding On Probing Index (BOP). Timepoint: At the beginning of the study and 14 days after starting mouthwash. Method of measurement: Using periodontal probe.;Modified Gingival Index (MGI). Timepoint: At the beginning of the study and 14 days after starting mouthwash. Method of measurement: Visual observation.;Plaque Index (PI). Timepoint: At the beginning of the study and 14 days after starting mouthwash. Method of measurement: Using periodontal probe, Loe and Silness method.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactReyhane Mousavi Neyshabouri

Mashhad University of Medical Sciences

MousaviNR931@mums.ac.ir+98 51 3881 9483

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026