Halitosis. Halitosis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Age range from 18 to 60 years Halitosis with an Organoleptic (OLT) score of two and above, which is subjectively determined by the doctor and objectively by the person herself Informed consent
Exclusion criteria
Exclusion criteria: The presence of infection and active inflammation of the nose and pharynx in examination and history History of sensitivity to probiotics The presence of infection and active inflammation of the mouth and teeth in examination and history Advanced renal failure Cirrhosis of the liver The patient's lack of consent to participate or the desire to withdraw from the study Use of immunosuppressive drugs Pregnancy and breastfeeding Use of mouthwash and mouth fresheners during the study Patients with typical symptoms GERD or peptic ulcer Use of antibiotics in the last month Recent surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of halitosis. Timepoint: before treatment (day zero); Day 15; Day 30 (end of treatment); Day 45 and Day 60. Method of measurement: based on organoleptic score. | — |
Secondary
| Measure | Time frame |
|---|---|
| Side effects. Timepoint: before treatment (day zero); Day 15; Day 30 (end of treatment). Method of measurement: evaluation checklist.;Remission rate. Timepoint: before treatment (day zero); Day 15; Day 30 (end of treatment); Day 45 and Day 60. Method of measurement: based on organoleptic score. | — |
Countries
Iran (Islamic Republic of)
Contacts
Mazandaran University of Medical Sciences