functional constipation. Constipation, unspecified
Conditions
Interventions
Intervention 1: Control group: standard treatment (15 gr of psyllium daily) for 30 days. Intervention 2: Intervention group: standard treatment and GeriLact Capsules (zist takhmir, Tehran, Iran) twice
Sponsors
Mazandaran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients with functional constipation according to Rome (III) criteria. Patients who do not change their diet during the study. Over 18 years
Exclusion criteria
Exclusion criteria: Depression systemic diseases such as diabetes, and inflammatory bowel disease Constipation due to hypothyroidism and hypercalcemia Surgeries such as prostate, bowel resection , and spine surgery Recent weight loss cancer Requiring colonoscopy Recent use of laxatives Pregnancy and lactation Alcohol and opium users Recent use of steroids, anticholinergics, antidepressants, iron, statins, cholestyramine, Cox-2 inhibitor, and sulfosalazine
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of constipation. Timepoint: At the beginning of the study (before the intervention), 15, 30, and 45 days after the beginning. Method of measurement: Wexner constipation Scoring System.;Stool consistency. Timepoint: At the beginning of the study (before the intervention), 15, 30, and 45 days after the beginning. Method of measurement: Bristol scoring system. | — |
Secondary
| Measure | Time frame |
|---|---|
| Side effects. Timepoint: At the beginning of the study (before the intervention), 15, 30, and 45 days after the beginning. Method of measurement: evaluation checklist.;Remission. Timepoint: At the beginning of the study (before the intervention), 15, 30, and 45 days after the beginning. Method of measurement: Total scores obtained from Wexner and Bristol systems. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactArash Kazemi
Mazandaran University of Medical Sciences
Outcome results
None listed