Congestive heart failure. Heart failure
Conditions
Interventions
Intervention 1: Intervention group: Lycopene, one 25 mg tablet daily, for 60 days, 21st Century company, made in USA, contains 25 mg of lycopene and 170 mg of calcium carbonate. Intervention 2: Contro
Sponsors
Islamic Azad University
Eligibility
Sex/Gender
Male
Age
40 Years to 70 Years
Inclusion criteria
Inclusion criteria: Patients with ischemic heart failure Age: 40 -70 years olds Ejection Fraction: 20 - 40
Exclusion criteria
Exclusion criteria: Patients with cancer, nephrotic diseases, diabetes, autoimmune diseases, organ transplantation, immunosuppressive drugs, bronchial diseases, stroke, arrhythmia, late surgery, active viral infection, active internal hemorrage, anemia with Hb<10g/dl Smoking
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Heart function. Timepoint: Before of intervention, 60 days after of intervention. Method of measurement: Echocardiogram.;Lipid profile. Timepoint: Before of intervention, 60 days after of intervention. Method of measurement: Auto analyzer biochemistry.;Total antioxidant capacity. Timepoint: Before of intervention, 60 days after of intervention. Method of measurement: Assay kit, Spectrophotometer.;Paraoxonase enzyme activity assay. Timepoint: Before of intervention, 60 days after of intervention. Method of measurement: Assay kit, Spectrophotometer.;Arylesterase enzyme activity assay. Timepoint: Before of intervention, 60 days after of intervention. Method of measurement: Assay kit, Spectrophotometer.;LDL separation from plasma. Timepoint: Before of intervention, 60 days after of intervention. Method of measurement: Ultracentrifuge.;Assessment of LDL oxidation. Timepoint: Before of intervention, 60 days after of intervention. Method of measurement: Cuso4, Spectrophotometer. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactLaila Rejali
Islamic Azad University
Outcome results
None listed