Polycystic ovarian syndrome. Polycystic ovarian syndrome
Conditions
Interventions
Intervention 1: Intervention group: ketogenic diet, in this group, the basic calorie amount of the participants is calculated through the formula of estimating the amount of energy consumed according
Duration of intervention: 4 weeks. Intervention 2: Control group: Low-carbohydrate portfolio diet, in this group, the basic calorie amount of the participants is calculated through the formula of esti
Sponsors
Kermanshah University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: All women with PCOS that diagnosed by a gynecologist based on the Rotterdam criteria, which includes having at least 2 of the 3 listed symptoms 1) Oligomenorrhea or amenorrhea 2) Biochemical or clinical symptoms of increased androgen levels in the blood 3) Having polycystic ovaries in ultrasound. Having a body mass index of 25-39.9 kg/m2 Having a desire to lose weight
Exclusion criteria
Exclusion criteria: Pregnancy Lactation Following special or low-calorie diets for at least the last three months Having diabetes Having adrenal gland disorders Having systematic or mental diseases Having thyroid diseases Taking drugs affecting carbohydrate or lipid metabolism Taking oral contraceptive pills Taking anti-epileptic pills Taking statins Fish oil consumption Use of fertility enhancing drugs or weight loss drugs Use of hormonal treatments or insulin sensitizing drugs in the last two months Having liver and kidney disease Having high blood pressure Having anemia Having severe respiratory diseases such as asthma and chronic inflammation of the bronchi Having cardiovascular diseases Having autoimmune diseases
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total cholesterol. Timepoint: At the beginning of the study (before the intervention) and at the end of the study. Method of measurement: Direct enzymatic method.;LDL cholesterol. Timepoint: At the beginning of the study (before the intervention) and at the end of the study. Method of measurement: Direct enzymatic method.;Fasting blood sugar. Timepoint: At the beginning of the study (before the intervention) and at the end of the study. Method of measurement: Glucose oxidase assay. | — |
Secondary
| Measure | Time frame |
|---|---|
| Weight. Timepoint: At the beginning of the study (before the intervention) and at the end of the study. Method of measurement: Measure with a scale.;Body mass index. Timepoint: At the beginning of the study (before the intervention) and at the end of the study. Method of measurement: Weight in kilograms divided by the square of height in meters.;Insulin. Timepoint: At the beginning of the study (before the intervention) and at the end of the study. Method of measurement: Enzyme-Linked Immunosorbent Assay.;Testosterone. Timepoint: At the beginning of the study (before the intervention) and at the end of the study. Method of measurement: Enzyme-Linked Immunosorbent Assay.;Luteinizing hormone. Timepoint: At the beginning of the study (before the intervention) and at the end of the study. Method of measurement: Enzyme-Linked Immunosorbent Assay.;Follicle stimulation hormone. Timepoint: At the beginning of the study (before the intervention) and at the end of the study. Method of measurement: Enzyme-Linked Immunosorbent Assay.;Dehydroepiandrosterone. Timepoint: At the beginning of the study (before the intervention) and at the end of the study. Method of measurement: Enzyme-Linked Immunosorbent Assay. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAmir Saber
Kermanshah University of Medical Sciences
Outcome results
None listed