"The effect of vitamin E on sperm in men with varicocele"

Effect of vitamin E on quality and quantity of sperm in infertile men after varicocelectomy .

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200911048689N1

Enrollment

Registered

2020-10-10

Start date

2020-09-22

Completion date

Unknown

Last updated

2020-11-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Varicocele. Scrotal varices

Interventions

Intervention 1: Intervention group: Vitamin E capsules with a dose of 400 units from Dana Pharmaceutical Company are taken once a day for 3 months after breakfast and with water. Intervention 2: Contr

Eligibility

Sex/Gender

Male

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Infertility due to palpable varicocele grade 2 and 3 Weight between 50 to 100 kg Being married

Exclusion criteria

Exclusion criteria: Absence of azoospermia Diabetes mellitus Hormonal diseases Smoking and addiction Daily use of multivitamins Urinary and genital infections History of gastric ulcer History of allergies and reactions to vitamins E Testicular atrophy

Design outcomes

Primary

Measure	Time frame
Variables in the spermogram include semen volume, sperm count, and sperm motility. Timepoint: Before the intervention and 3 months after the intervention. Method of measurement: Using spermogram parameters and comparison with the amount recommended by the World Health Organization.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactKasra Saeedian

Mashhad University of Medical Sciences

saeidiank931@mums.ac.ir+98 21 8881 1033

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 6, 2026