Comparison of the effect of Lidocaine and Granisetron on postoperative nausea and vomiting

Comparison of the effect of Lidocaine and Granisetron on postoperative nausea and vomiting in laparoscopic cholecystectomy

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200910048678N1

Enrollment

120

Registered

2020-12-01

Start date

2020-09-19

Completion date

Unknown

Last updated

2021-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cholecystitis. Cholecystitis, unspecified

Interventions

Intervention 1: Patients in intervention group 1, at the end of the surgery (after discontinuation of anesthetic drugs) and before extubation, receiving 1.5 mg/kg of lidocain 2% (manufactured by Caspi

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age>18 year American Society of Anesthesiologists Class (ASA Class) I & II No history of motion sickness No history of drug allergy Laparoscopic cholecystectomy under general anesthesia Body Mass Index (BMI) <30 Non-smoking Not receiving anti-nausea medication in the last 24 hours

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Postoperative nausea. Timepoint: Recovery, 6, 12 and 24 hours after surgery. Method of measurement: Rhodes Questionnaire, Visual Analogue Scale.;Postoperative vomiting. Timepoint: Recovery, 6, 12 and 24 hours after surgery. Method of measurement: Rhodes Questionnaire, Visual Analogue Scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyede Fatemeh Gheiasi

Zanjan University of Medical Sciences

fatemeh.gheiasi@zums.ac.ir+98 24 3314 8338

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026