COVID-19. COVID-19
Conditions
Interventions
Intervention 1: Intervention group: 40 patients receiving routine + celecoxib treatments. This group is divided into two subgroups (20 people in each group):A dose received 200mg / day (in divided dos
Sponsors
Zahedan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Subjects with COVID-19 in the second phase of the disease Shortness of breath, chest pain with or without fever equal to or greater than 38 'C Blood oxygen saturation (SpO2) between 90-93% Adult patients with COVID-19 with moderate pulmonary involvement and hospitalized in the general ward who have been diagnosed and confirmed with coronavirus by conventional diagnostic methods such as sequencing or qRT-PCR and CT (within 48 hours of admission) Age range of patients between 18-65 years Existence of pneumonia in lung CT scan with involvement of maximum 3 or 4 lung lobes or less than one third of the volume of each lobe or infection of one or two lobes with larger area Patients informed consent
Exclusion criteria
Exclusion criteria: Patients under 18 or over 65 years old Patients with severe and advanced disease are admitted to the intensive care unit Participate in another clinical trial Shock and critical illness (requires ventilator and organ failure) Patients with organ dysfunction such as renal failure and liver damage, patients with asthma Taking certain medications such as furosemide or Lasex, lithium, ACE2 inhibitors Pregnancy People with medical history such as high blood pressure, autoimmune diseases and ..
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lung function (Pulmonary infiltration, GGO, Edema). Timepoint: Every week. Method of measurement: CT Scan.;Respiratory Rate, SpO2, PaO2/FiO2. Timepoint: Every day. Method of measurement: Physical examination.;Body Temperature. Timepoint: Every day. Method of measurement: Thermometer. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactRoghayh Sheervalilou
Zahedan University of Medical Sciences
Outcome results
None listed