Comparison of three-drug and consecutive treatment regimens in the eradication of Helicobacter pylori in patients referred to the gastrointestinal clinic of Imam Khomeini Hospital in Urmia

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200907048643N1

Enrollment

270

Registered

2020-09-14

Start date

2018-03-21

Completion date

Unknown

Last updated

2020-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Comparison of three-drug and consecutive treatment regimens in eradication of Helicobacter pylori in patients referred to the gastrointestinal clinic of Imam Khomeini Hospital in Urmia. Oesophagitis

Interventions

Intervention 1: Intervention group: First group: omeprazole 20mg twice daily + amoxicillin one gram twice daily + clarithromycin 500mg twice daily for 10 days Second group: omeprazole 20mg twice daily

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1- Endoscopic primary infection of Helicobacter pylori 2-Have symptoms of dyspepsia for at least 6 months or more 3- No history of taking any antibiotics during the last month and no history of taking proton and antacid pump inhibitors in the last month

Exclusion criteria

Exclusion criteria: 1- Endoscopic primary infection of Helicobacter pylori 2-Have symptoms of dyspepsia for at least 6 months or more 3- No history of taking any antibiotics during the last month and no history of taking proton and antacid pump inhibitors in the last month

Design outcomes

Primary

Measure	Time frame
Helicobacter pylori treatment. Timepoint: Patients were referred to the clinic 2 weeks, 6 weeks and 10 weeks after starting treatment. Patients were examined for Helicobacter pylori by Stool Ag test. Individuals who were registered for successful negative test treatment for H. pylori eradication. In the second week visit, all side effects including (bad taste, dry mouth, diarrhea, confusion, tongue burn, nausea and vomiting, abdominal pain, constipation and headache) and patient compliance were recorded based on the number of pills remaining and then four weeks PPI only It was taken and then they did not take any PPI and antibiotics for 4 weeks and then it was proved by Stool Ag eradication of Helicobacter pylori infection in each group. Method of measurement: Blood and stool tests.	—

Measure

Time frame

Helicobacter pylori treatment. Timepoint: Patients were referred to the clinic 2 weeks, 6 weeks and 10 weeks after starting treatment. Patients were examined for Helicobacter pylori by Stool Ag test. Individuals who were registered for successful negative test treatment for H. pylori eradication. In the second week visit, all side effects including (bad taste, dry mouth, diarrhea, confusion, tongue burn, nausea and vomiting, abdominal pain, constipation and headache) and patient compliance were recorded based on the number of pills remaining and then four weeks PPI only It was taken and then they did not take any PPI and antibiotics for 4 weeks and then it was proved by Stool Ag eradication of Helicobacter pylori infection in each group. Method of measurement: Blood and stool tests.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHamid Reza Mehryar

Oroumia University of Medical Sciences

omid.garkaz23@gmail.com+98 44 3223 4897

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026