acyclovir in anal fissure

Evaluation and comparison of therapeutic results of acyclovir in the treatment and improvement of anal fissure in non-herpes simplex virus patients and control group

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200906048636N1

Enrollment

120

Registered

2021-12-29

Start date

2021-12-06

Completion date

Unknown

Last updated

2022-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anal fissures. Anal fissure, unspecified

Interventions

Intervention 1: Intervention group: First group receiving acyclovir ointment as treatment of anal fissure. Intervention 2: Control group: Second group receiving common treatment (diltiazem ointment) o

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients' informed consent to participate in the study No previous or current history of HSV and other STDs Adults over the age of 18 Referral patients with clinical diagnosis of anal fissure

Exclusion criteria

Exclusion criteria: Have a previous or current history of HSV and other perinatal STDs Patient dissatisfaction to participate in the study

Design outcomes

Primary

Measure	Time frame
Pain relief assessed based on numerical rating scale (NRS). Timepoint: before intervention and 2, 3 , 4, 8, 12 weeks after intervention. Method of measurement: Checklist based on NRS.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAli Farbod

Tabriz University of Medical Sciences

ali.frbd@gmail.com0098413331317

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026