Reducedovarian reserve.. Primary ovarian failure
Conditions
Interventions
Intervention 1: Intervention group: 29 infertile women with reduced ovarian reserve between 18 and 45 years of age with the administration of platelet-rich plasma alone, which is prepared and injected
Sponsors
Bandare-abbas University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: Informed consent of the patient (completion of the patient consent form by the patient or the patient's companion) Patients aged 18 to 45 years. Patients who have no history of ovarian surgery or ovarian endometrioma. Normal sperm analysis • POR (age over 40 years and/or a history of poor response to high-dose stimulation with less than three oocytes and/or adverse ovarian reserve tests including AMH < 1.1 ng/nl; AFC < 7) Patients without endocrine disorders such as hyperprolactinemia, PCOS, etc. Non-smoking patients Patients who do not have cardiovascular disorders.
Exclusion criteria
Exclusion criteria: Adhesion or severe damage to the pelvis or ovaries Immunological diseases Hematological diseases Platelets less than one hundred and fifty thousand per cubic millimeter Systemic use of corticosteroids within two weeks before the procedure Taking anticoagulants
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The number of retrieved oocytes. Timepoint: Two months after prp injection. Method of measurement: Count the number.;The number of MII oocyte obtained. Timepoint: Two months after prp injection. Method of measurement: Count the number.;Increase in AMH. Timepoint: The day of the prp injection, and then two months after the prp injection. Method of measurement: laboratory test. | — |
Secondary
| Measure | Time frame |
|---|---|
| IVF cycle cancellation rate. Timepoint: Two months after PRP injection. Method of measurement: Count the number.;Clinical pregnancy rate. Timepoint: 6 weeks after embryo transfer. Method of measurement: Vaginal ultrasound.;Live birth rate. Timepoint: 9 months after embryo transfer. Method of measurement: Count the number.;Ongoing pregnancy rate. Timepoint: 20 weeks after embryo transfer. Method of measurement: Ultrasound. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Maryam Azizi Kutenaee
Bandare-abbas University of Medical Sciences
Outcome results
None listed