The effect of serum progesterone on third day after intrauterine insemination (IUI) on pregnancy outcomes in two different methods of progesterone administration

Evaluation of serum progesterone level on third day after intrauterine insemination on pregnancy outcomes in two routes of luteal phase support in women with unexplained infertility : A randomized clinical trial study.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200905048630N3

Enrollment

140

Registered

2021-11-22

Start date

2021-08-23

Completion date

Unknown

Last updated

2021-11-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility.

Interventions

Intervention 1: Intervention group:receiving vaginal progesterone( crinone gel 8%), Crinone gel contains 90 mg of progesterone and is consumed once a day for 14 days. Intervention 2: Control group: r

Eligibility

Sex/Gender

Female

Age

18 Years to 37 Years

Inclusion criteria

Inclusion criteria: IUI cycles Patients with normal uterine cavity

Exclusion criteria

Exclusion criteria: Patients with uterine abnormalities such as myoma, anatomical problems, polyp, salpangitis Patients with a history of recurrent miscarriage Age over 37 years old Patients with grade 3 or 4 endometriosis BMI over 30 kg/m2 Previous ectopic pregnancy Usage two type of progesterone for luteal phase support Endometrial thickness lower than 7mm on trigger day

Design outcomes

Primary

Measure	Time frame
Biochemical pregnancy. Timepoint: 14 days after IUI. Method of measurement: Beta serum level evaluation.;Biochemical pregnancy. Timepoint: 8 weeks after IUI. Method of measurement: Sonography.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Maryam azizi kutenaee

Bandare-abbas University of Medical Sciences

maryamazizikut86@gmail.com+98 76 3333 0755

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026