polycystic ovary syndrome. Polycystic ovarian syndrome
Conditions
Interventions
Intervention 1: Intervention group: Control group: From the beginning of the monthly cycle, they take 1 mg of folic acid tablets and one empty capsule (placebo) daily. The use of this pill and placebo
Sponsors
Gonabad University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 35 Years
Inclusion criteria
Inclusion criteria: Age 18 to 35 years Having written consent to participate in the study Infertility is known to cause polycystic ovary syndrome and rule out other causes of infertility Ultrasound-confirmed polycystic ovaries along with another Rotterdam criteria No other androgenic disorders such as adrenal hyperplasia or androgen-producing tumor Manifestations of hyperandrogenism (high testosterone) No diseases such as: hypothyroidism or hyperthyroidism, hyperprolactinemia, kidney, heart, liver, bone diseases, pituitary tumor, cancer and diabetes Do not take infertility drugs or any other hormonal drugs in the last three months Body mass index 18 to 35 Hypersensitivity to food and drugs such as lactose, letrozole and vitagnus
Exclusion criteria
Exclusion criteria: Breastfeeding Smoking and drugse Stressful events in the last three months Previous surgery on one or both ovaries Taking haloperidol
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of follicles. Timepoint: Before the intervention and 1/5 month after the intervention. Method of measurement: Sonography.;Follicle size. Timepoint: Before the intervention and 1/5 month after the intervention. Method of measurement: Sonography.;Endometrial thickness. Timepoint: Before the intervention and 1/5 month after the intervention. Method of measurement: Sonography.;Fertility rate. Timepoint: Before intervention and 2 months after intervention. Method of measurement: BHCG test. | — |
Secondary
| Measure | Time frame |
|---|---|
| Improve ovarian function. Timepoint: After the intervention. Method of measurement: sonography.;Side effects. Timepoint: During and after the intervention. Method of measurement: check list. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactVahideh Behmard
Gonabad University of Medical Sciences
Outcome results
None listed