Effect of Respiratory Muscle Training in Multiple Sclerosis

Evaluation the Effect of 8 Weeks Respiratory Muscle Training on Respiratory Capacity, Functional Capacity and Quality of Life on Subjects with Mild to Moderate Relapsing Remitting Multiple Sclerosis

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200827048542N1

Enrollment

Registered

2020-10-25

Start date

2020-10-22

Completion date

Unknown

Last updated

2020-11-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multiple Sclerosis. Multiple sclerosis

Interventions

Intervention 1: Intervention group:?They will educated respiratory muscle training with a pressure threshold device (Power-breath), then patients will do exercises for 8 weeks. During this time, patie

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Definite diagnosed relapsing-remitting MS Year after diagnosed at least one year Be able to walk without support at least 10 meters Not have an relapse at least one month Taking no intravenous corticosteroid drug

Exclusion criteria

Exclusion criteria: history of any respiratory disease have an active pulmonary infection Contraindicated for aerobic activity (such as orthopedic and muscular problem) smoker pregnancy Participate in another research program

Design outcomes

Primary

Measure	Time frame
Maximum Inspiratory Pressure. Timepoint: before intervention and 8 weeks after intervention. Method of measurement: Body Box machine.;Maximum Expiratory Pressure. Timepoint: before intervention and 8 weeks after intervention. Method of measurement: Body Box machine.	—

Secondary

Measure	Time frame
Quality of Life. Timepoint: before intervention and 8 weeks after intervention. Method of measurement: SF-36 questionnaire.;Aerobic capacity. Timepoint: before intervention and 8 weeks after intervention. Method of measurement: Six Minute Walk Test (6MWT).;Functional capacity. Timepoint: before intervention and 8 weeks after intervention. Method of measurement: Timed Up and Go test (TUG).;Forced Expiratory volume in the first second (FEV1). Timepoint: before intervention and 8 weeks after interventio. Method of measurement: Spirometry.;Forced Expiratory volume in the first second (FEV1)/Forced Vital Capacity (FVC). Timepoint: before intervention and 8 weeks after intervention. Method of measurement: Spirometry.;Fatigue. Timepoint: before intervention and 8 weeks after intervention. Method of measurement: Modified Fatigue Impact Scale questionnaire (MFIS).	—

Measure

Time frame

Quality of Life. Timepoint: before intervention and 8 weeks after intervention. Method of measurement: SF-36 questionnaire.;Aerobic capacity. Timepoint: before intervention and 8 weeks after intervention. Method of measurement: Six Minute Walk Test (6MWT).;Functional capacity. Timepoint: before intervention and 8 weeks after intervention. Method of measurement: Timed Up and Go test (TUG).;Forced Expiratory volume in the first second (FEV1). Timepoint: before intervention and 8 weeks after interventio. Method of measurement: Spirometry.;Forced Expiratory volume in the first second (FEV1)/Forced Vital Capacity (FVC). Timepoint: before intervention and 8 weeks after intervention. Method of measurement: Spirometry.;Fatigue. Timepoint: before intervention and 8 weeks after intervention. Method of measurement: Modified Fatigue Impact Scale questionnaire (MFIS).

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactShima Ghannadi

Tehran University of Medical Sciences

Sh_ghannadi90@yahoo.com+98 21 8863 0227

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026