Cardiopulmonary Bypass Surgery. Atherosclerotic heart disease of native coronary artery
Conditions
Interventions
Intervention 1: First Intervention group: In this group, the blood flow of the patients will be regulated in a pulsatile (pulsed) manner using a heart-lung machine (CPB). Intervention 2: Second Interv
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Age between 18 and 80 years EF greater than 45% Normal renal function No chronic renal disease Written informed consent
Exclusion criteria
Exclusion criteria: Emergency surgery Receiving medications that affect urine volume (such as furosemide, hydrochlorothiazide) within 24 hours before surgery, during surgery, or within 24 hours after surgery Requirement for intra-aortic balloon pump (IABP) or other mechanical support prior to surgery Severe underlying disease such as chronic liver and kidney failure or pulmonary disease Cardiopulmonary pump shutdown before perfusion
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Urine volume. Timepoint: In the first 24 hours before surgery. Method of measurement: Measurement of urine volume in the patient's urine bag.;Creatinine. Timepoint: Before and after surgery. Method of measurement: Laboratory test.;Acute kidney injury. Timepoint: During hospitalization. Method of measurement: According to KDIGO criteria (0.3 mg/dL increase in serum creatinine or greater than 1.5-fold relative change from baseline). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMehran Shahzamani
Esfahan University of Medical Sciences
Outcome results
None listed