Prostate cancer. Malignant neoplasm of prostate
Conditions
Interventions
Intervention 1: First intervention group: In addition to radiotherapy, this group will be administered a probiotic sachet orally daily for one week. They will also receive placebo tablets orally for o
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
Male
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients with prostate cancer, requiring radiotherapy with tumor therapy Age group 18 years and above No concurrent radiotherapy with chemotherapy No deep ulcer or rectal stenosis and fistula formation No chronic diarrhea before starting radiotherapy No inflammatory bowel diseases such as IBD, Crohn's, ulcerative colitis No use of narcotics Consent to enter the study
Exclusion criteria
Exclusion criteria: Use of antibiotics before entering the study Having history of previous pelvic radiotherapy Having allergy to the study drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Acute intestinal complications. Timepoint: Before intervention, 8 and 12 weeks after intervention. Method of measurement: Based on the criteria of European Organisation for Research and Treatment of Cancer/Radiation Therapy Oncology Group (RTOG/EORTC).;Digestive symptoms. Timepoint: Before intervention, 8 and 12 weeks after intervention. Method of measurement: Scale of gastrointestinal symptom rating scale (GSRS). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactNadia Najafizade
Esfarayen University of Medical Sciences
Outcome results
None listed