Elective surgery. Surgical procedure, unspecified as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
Conditions
Interventions
Intervention 1: The first intervention group: Induction of anesthesia in patients with propofol (2 mg/kg), fentanyl 2 µg/kg and atracurium (0.5 mg/kg). Then, in this group, normal saline 70 cc will be
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 60 Years
Inclusion criteria
Inclusion criteria: Candidate for elective surgery under general anesthesia Age range from 20 to 60 years American Society of Anesthesiologists (ASA) class equal to 1 or 2 Weight 55 to 85 kg (body mass index 18.5-24.9 kg/m2) Consent to participate in the study
Exclusion criteria
Exclusion criteria: Pregnancy Having underlying diseases (including diabetes, chronic lung disease, cardiovascular disease, uncontrolled blood pressure, kidney failure) Having a heart rate of less than 60 beats/minute or a systolic blood pressure of less than 90 mmHg upon entering the study. Having an allergy to the drugs used Drug use
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Systolic blood pressure. Timepoint: Before induction of anesthesia, before extubation, 1, 3, 5, and 10 minutes after extubation. Method of measurement: Monitoring device.;Diastolic blood pressure. Timepoint: Before induction of anesthesia, before extubation, 1, 3, 5, and 10 minutes after extubation. Method of measurement: Monitoring device.;Heart rate. Timepoint: Before induction of anesthesia, before extubation, 1, 3, 5, and 10 minutes after extubation. Method of measurement: Monitoring device.;Oxygen saturation (SPO2). Timepoint: Before induction of anesthesia, before extubation, 1, 3, 5, and 10 minutes after extubation. Method of measurement: Monitoring device. | — |
Secondary
| Measure | Time frame |
|---|---|
| Tachycardia. Timepoint: before induction of anesthesia, before extubation, 1, 3, 5, and 10 minutes after extubation. Method of measurement: Heart rate more than 100 beats per minute.;Bradycardia. Timepoint: before induction of anesthesia, before extubation, 1, 3, 5, and 10 minutes after extubation. Method of measurement: Heart rate less than 60 beats per minute.;Cough. Timepoint: After extubation. Method of measurement: Observation.;Laryngospasm. Timepoint: After extubation. Method of measurement: Observation.;Hypoxia. Timepoint: After extubation. Method of measurement: Oxygen less than 60 bpm. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHamidreza Shetabi
Esfahan University of Medical Sciences
Outcome results
None listed