Comparison of the effects of two different doses of dexmedomidine and propofol in sedation during ovarian surgery

Comparing the effect of two different doses of dexmedetomidine and propofol in sedation during surgery; Hemodynamic changes and postoperative complications in patients undergoing ovarian puncture surgery

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200825048515N73

Enrollment

Registered

2024-02-16

Start date

2024-03-20

Completion date

Unknown

Last updated

2024-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ovarian puncture surgery.

Interventions

Intervention 1: Control group: in this group, propofol induction of anesthesia 50 µg/kg per minute is prescribed. Intervention 2: First intervention group: In this group, dexmedetomidine bolus dose of

Eligibility

Sex/Gender

All

Age

25 Years to 43 Years

Inclusion criteria

Inclusion criteria: Infertile women candidates for puncture operation with IVF/ICSI indication Age 25 to 43 years With ASA I or II Consent to enter the study

Exclusion criteria

Exclusion criteria: Having an allergy to any drug used Having a history of diseases such as epilepsy and gastric reflux and a history of severe cardiovascular disease and the presence of atrial block or stroke

Design outcomes

Primary

Measure	Time frame
Sedation. Timepoint: Before the intervention and then 5, 10, 15 and 30 minutes after the intervention and then every 15 minutes during recovery until discharge. Method of measurement: Richmond sedation score scale (RASS) as a score of +4 to -5.;Hear rate. Timepoint: Before the intervention and then 5, 10, 15 and 30 minutes after the intervention and then every 15 minutes during recovery until discharge. Method of measurement: Monitoring device.;Diastolic blood pressure. Timepoint: Before the intervention and then 5, 10, 15 and 30 minutes after the intervention and then every 15 minutes during recovery until discharge. Method of measurement: Monitoring device.;Systolic blood pressure. Timepoint: Before the intervention and then 5, 10, 15 and 30 minutes after the intervention and then every 15 minutes during recovery until discharge. Method of measurement: Monitoring device.	—

Measure

Time frame

Sedation. Timepoint: Before the intervention and then 5, 10, 15 and 30 minutes after the intervention and then every 15 minutes during recovery until discharge. Method of measurement: Richmond sedation score scale (RASS) as a score of +4 to -5.;Hear rate. Timepoint: Before the intervention and then 5, 10, 15 and 30 minutes after the intervention and then every 15 minutes during recovery until discharge. Method of measurement: Monitoring device.;Diastolic blood pressure. Timepoint: Before the intervention and then 5, 10, 15 and 30 minutes after the intervention and then every 15 minutes during recovery until discharge. Method of measurement: Monitoring device.;Systolic blood pressure. Timepoint: Before the intervention and then 5, 10, 15 and 30 minutes after the intervention and then every 15 minutes during recovery until discharge. Method of measurement: Monitoring device.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammadreza Habibzadeh

Esfahan University of Medical Sciences

M.habibzadeh@med.mui.ac.ir+98 31 3620 2020

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026