Surgical coronary artery bypass graft. Presence of cardiac and vascular implant and graft, unspecified
Conditions
Interventions
Intervention 1: First intervention group: In this group, gabapentin 300 mg is given orally to the patients one hour before surgery. And after surgery 300 mg every 8 hours in ICU for three days. Interv
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
No minimum to 40 Years
Inclusion criteria
Inclusion criteria: Patients who are candidates for elective heart surgery Age category above 40 years EF>40% American Society of Anesthesiologists (ASA) level III
Exclusion criteria
Exclusion criteria: Addiction to drugs, alcohol and industrial psychotropic substances History of taking antipsychotic and antidepressant drugs Having liver and kidney diseases Allergy to paracetamol and gabapentin drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood pressure. Timepoint: During operation every 15 minutes and in ICU every 1 hour. Method of measurement: Monitoring device.;Heart rate. Timepoint: During operation every 15 minutes and in ICU every 1 hour. Method of measurement: Monitoring device.;Pain. Timepoint: Post-operatively in the ICU. Method of measurement: Visual analog scale (VAS). | — |
Secondary
| Measure | Time frame |
|---|---|
| Nausea and vomiting. Timepoint: After surgery in recovery or ICU. Method of measurement: Observation.;Constipation. Timepoint: After surgery in recovery or ICU. Method of measurement: Observation.;Delirium. Timepoint: After surgery in recovery or ICU. Method of measurement: Observation. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMojtaba Mansouri
Esfahan University of Medical Sciences
Outcome results
None listed