Effect of respiratory tidal volume on the required dose of remifentanil to create controlled hypotension

The effect of respiratory tidal volume on the required dose of remifentanil to create controlled hypotension in rhinoplasty surgery

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200825048515N71

Enrollment

Registered

2023-10-08

Start date

2023-10-22

Completion date

Unknown

Last updated

2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rhinoplasty. Other and unspecified disorders of nose and nasal sinuses

Interventions

Intervention 1: First intervention group: In this group, the minimum tidal volume is selected based on the ideal weight (6 cc/kg). Then remifentanil (according to routine) is given to cause hypotensio

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Candidate patients for rhinoplasty Age group 18-65 years Weight more than 50 kg American Society of Anesthesiologists (ASA) class is equal to I Informed consent to participate in the study

Exclusion criteria

Exclusion criteria: Being addicted to opioid products Having the comorbidity (such as respiratory and coagulation disease) History of allergy to the studied drug

Design outcomes

Primary

Measure	Time frame
Blood pressure. Timepoint: Before surgery, immediately before anesthesia and every 10 minutes during surgery until the end of surgery. Method of measurement: Monitoring device.;Blood pressure. Timepoint: Before surgery, immediately before anesthesia and every 10 minutes during surgery until the end of surgery. Method of measurement: Monitoring device.;Satisfaction. Timepoint: End of surgery. Method of measurement: Visual Analogue Scale (VAS).	—

Measure

Time frame

Blood pressure. Timepoint: Before surgery, immediately before anesthesia and every 10 minutes during surgery until the end of surgery. Method of measurement: Monitoring device.;Blood pressure. Timepoint: Before surgery, immediately before anesthesia and every 10 minutes during surgery until the end of surgery. Method of measurement: Monitoring device.;Satisfaction. Timepoint: End of surgery. Method of measurement: Visual Analogue Scale (VAS).

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAlireza Hoghooghi

Esfahan University of Medical Sciences

alireza.hoghooghy@gmail.com+98 31 3620 2020

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026