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The effect of lidocaine and ketamine on pain after upper limb orthopedic surgery

Investigating the preventive effect of lidocaine infusion and ketamine infusion on pain after upper limb orthopedic surgery under general anesthesia

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200825048515N68
Enrollment
180
Registered
2023-06-14
Start date
2023-07-21
Completion date
Unknown
Last updated
2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Upper extremity orthopedic surgery.

Interventions

Intervention 1: First intervention group: patients in this group will be injected with lidocaine infusion at a low dose (1 mg/kg/hour) at the end of the operation. Intervention 2: Second intervention

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Candidate patients for elective upper extremity orthopedic surgery under general anesthesia Age 65-18 years Informed consent to participate in this study

Exclusion criteria

Exclusion criteria: Addiction to opioid products Having an underlying disease (hypertension and uncontrolled diabetes or any neurological disorder) that has led to impaired sensation or movement of the operated organ Hypersensitivity to lidocaine or ketamine

Design outcomes

Primary

MeasureTime frame
Mean arterial pressure. Timepoint: In the basic times, the first hour every 15 minutes, the second hour every 30 minutes, the next 4 hours every 1 hour and after that every 2 hours for 24 hours. Method of measurement: Monitoring device.;Heart beat. Timepoint: In the basic times, the first hour every 15 minutes, the second hour every 30 minutes, the next 4 hours every 1 hour and after that every 2 hours for 24 hours. Method of measurement: Monitoring device.;Oxygen saturation percentage (SPO2). Timepoint: In the basic times, the first hour every 15 minutes, the second hour every 30 minutes, the next 4 hours every 1 hour and after that every 2 hours for 24 hours. Method of measurement: Monitoring device.;Pain. Timepoint: In the basic times, the first hour every 15 minutes, the second hour every 30 minutes, the next 4 hours every 1 hour and after that every 2 hours for 24 hours. Method of measurement: Visual Analogue Scale (VAS).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAlireza Hoghooghi

Esfahan University of Medical Sciences

alireza.hoghooghy@gmail.com+98 31 3620 2020

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026