The effect of continuous administration of two doses of sufentanil on changes in heart rate and blood pressure after laryngoscopy and tracheal intubation

A comparative study of the effect of two doses of sufentanil continuous infusion on changes in heart rate and blood pressure after laryngoscopy and tracheal intubation.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200825048515N62

Enrollment

Registered

2022-11-06

Start date

2022-11-22

Completion date

Unknown

Last updated

2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients requiring tracheal intubation for general anesthesia.

Interventions

Intervention 1: First Intervention group: In this group, anesthesia is induced within 60 seconds using sodium thiopental 5 mg/kg, lidocaine 1.5 mg/kg, atracurium 0.6 mg/kg, and sufentanil with a dose

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Age range from 18 to 65 years American Society of Anesthesiologists (ASA) I Requires tracheal intubation for general anesthesia Consent to participate in the study

Exclusion criteria

Exclusion criteria: Having heart failure Having a systolic blood pressure of less than 14 mmHg and diastolic blood pressure of 9 mmHg Having respiratory, liver, kidney failure Having airway malformations having an addiction

Design outcomes

Primary

Measure	Time frame
Systolic blood pressure. Timepoint: Baseline time, before laryngoscopy, 1, 3, 10 minutes after laryngoscopy. Method of measurement: Ventilation device.;Diastolic blood pressure. Timepoint: Baseline time, before laryngoscopy, 1, 3, 10 minutes after laryngoscopy. Method of measurement: Ventilation device.;Heart beat. Timepoint: Baseline time, before laryngoscopy, 1, 3, 10 minutes after laryngoscopy. Method of measurement: Ventilation device.;Oxygen saturation (SPO2). Timepoint: Baseline time, before laryngoscopy, 1, 3, 10 minutes after laryngoscopy. Method of measurement: Ventilation device.	—

Measure

Time frame

Systolic blood pressure. Timepoint: Baseline time, before laryngoscopy, 1, 3, 10 minutes after laryngoscopy. Method of measurement: Ventilation device.;Diastolic blood pressure. Timepoint: Baseline time, before laryngoscopy, 1, 3, 10 minutes after laryngoscopy. Method of measurement: Ventilation device.;Heart beat. Timepoint: Baseline time, before laryngoscopy, 1, 3, 10 minutes after laryngoscopy. Method of measurement: Ventilation device.;Oxygen saturation (SPO2). Timepoint: Baseline time, before laryngoscopy, 1, 3, 10 minutes after laryngoscopy. Method of measurement: Ventilation device.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAzim Honarmand

Esfahan University of Medical Sciences

honarmand@med.mui.a.ir+98 31 3620 2020

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026