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Comparison of the therapeutic effects of minoxidil solution alone with the combination of minoxidil and flutamide solution in patients with androgenic alopecia

Comparison of therapeutic effects of 5% minoxidil solution alone with the combination of 5% minoxidil and flutamide solution in patients with androgenic alopecia

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200825048515N6
Enrollment
40
Registered
2020-10-07
Start date
2020-10-22
Completion date
Unknown
Last updated
2020-11-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Androgenic alopecia. Androgenic alopecia, unspecified

Interventions

Intervention 1: Intervention group: Patients in the first intervention group will take 1 cc (equivalent to 20 drops) of 5% minoxidil solution twice a day for 9 months. Intervention 2: Intervention gro

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Confirmation of androgenic alopecia by two experienced dermatologists based on Hamilton diagnostic criteria Patient consent to participate in the study The intensity of hair loss in stage 2 to 5 according to Hamilton scale and in stages 1 and 2 according to Ludwig scale The duration of hair loss is less than 10 years

Exclusion criteria

Exclusion criteria: History or observation of allergies to any of the drugs minoxidil and flutamide History of heart disease and use of antihypertensive drugs Receiving systemic treatment for androgenic alopecia during the 6 months prior to the study Other types of alopecia such as alopecia areata, telogen effluvium, anagen effluvium and scarring alopecia of any systemic cutaneous disease

Design outcomes

Primary

MeasureTime frame
Hair density. Timepoint: Pre-and post-intervention. Method of measurement: Hair polarizer.;Severity of hair loss. Timepoint: Pre-and post-intervention. Method of measurement: By a skilled physician based on Hamilton-Norwood scale for male pattern hair loss and Ludwig scale for female pattern hair loss.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactGita Faghihi

Esfahan University of Medical Sciences

g_faghighi@med.mui.ac.ir+98 31 3620 2020

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026