Evaluation of therapeutic effects of adding memantine to stimulants in children with attention deficit hyperactivity disorder

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200825048515N58

Enrollment

Registered

2022-09-05

Start date

2022-09-23

Completion date

Unknown

Last updated

2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Attention-deficit hyperactivity disorder (ADHD). Attention-deficit hyperactivity disorder, unspecified type

Interventions

Intervention 1: Intervention group: Patients in this group receive their routine treatment. In addition, they will be treated with memantine. The prescribed dose in children is based on weight, so tha

Eligibility

Sex/Gender

All

Age

6 Years to 12 Years

Inclusion criteria

Inclusion criteria: Children with attention deficit hyperactivity disorder (ADHD) Age range 6 to 12 years Treated with methylphenidate Parents' consent to participate in the study

Exclusion criteria

Exclusion criteria: Having major medical disorders (diabetes, asthma, heart disease, seizures) Having a concomitant psychiatric disorder (mood and anxiety disorders and behavioral and confrontational disorders - disobedience) Taking another drug in addition to a long-acting stimulant Mental retardation Drug sensitivity

Design outcomes

Primary

Measure	Time frame
Cognitive Problems. Timepoint: Before and after the intervention. Method of measurement: The Conners' Parent Rating Scale (CPRS).;Social problems. Timepoint: Before and after the intervention. Method of measurement: The Conners' Parent Rating Scale (CPRS).;Psychosomatic problems. Timepoint: Before and after the intervention. Method of measurement: The Conners' Parent Rating Scale (CPRS).;Anxiety-shyness. Timepoint: Before and after the intervention. Method of measurement: The Conners' Parent Rating Scale (CPRS).;Inhibitory control. Timepoint: Before and after the intervention. Method of measurement: BREIF scale.;Emotional modulation. Timepoint: Before and after the intervention. Method of measurement: BREIF scale.;Ability to shift set. Timepoint: Before and after the intervention. Method of measurement: BREIF scale.;Working memory. Timepoint: Before and after the intervention. Method of measurement: BREIF scale.;Initiating. Timepoint: Before and after the intervention. Method of measurement: BREIF scale.;Planning. Timepoint: Before and after the intervention. Method of measurement: BREIF scale.;Organizing. Timepoint: Before and after the intervention. Method of measurement: BREIF scale.	—

Measure

Time frame

Cognitive Problems. Timepoint: Before and after the intervention. Method of measurement: The Conners' Parent Rating Scale (CPRS).;Social problems. Timepoint: Before and after the intervention. Method of measurement: The Conners' Parent Rating Scale (CPRS).;Psychosomatic problems. Timepoint: Before and after the intervention. Method of measurement: The Conners' Parent Rating Scale (CPRS).;Anxiety-shyness. Timepoint: Before and after the intervention. Method of measurement: The Conners' Parent Rating Scale (CPRS).;Inhibitory control. Timepoint: Before and after the intervention. Method of measurement: BREIF scale.;Emotional modulation. Timepoint: Before and after the intervention. Method of measurement: BREIF scale.;Ability to shift set. Timepoint: Before and after the intervention. Method of measurement: BREIF scale.;Working memory. Timepoint: Before and after the intervention. Method of measurement: BREIF scale.;Initiating. Timepoint: Before and after the intervention. Method of measurement: BREIF scale.;Planning. Timepoint: Before and after the intervention. Method of measurement: BREIF scale.;Organizing. Timepoint: Before and after the intervention. Method of measurement: BREIF scale.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactFarnaz Golmohammadi

Esfahan University of Medical Sciences

Farnazgolmohammadi@gmail.com+98 31 3386 6266

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026