Comparison of administration of low dose ketamine with lidocaine on changes in heart rate and blood pressure during intubation

A comparative study of administration of low dose ketamine with lidocaine on changes in heart rate and blood pressure during tracheal intubation under general anesthesia.

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200825048515N56

Enrollment

Registered

2022-07-17

Start date

2022-08-22

Completion date

Unknown

Last updated

2022-08-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Candidate patients for surgery under general anesthesia.

Interventions

Intervention 1: First intervention group: patients in this group receive 0.5 mg/kg of ketamine. Intervention 2: Second intervention group: patients in this group receive 0.5 mg/kg of lidocaine. Interv

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Age group 18 to 65 years American Society of Anesthesiologists (ASA) classification equal to one or two Candidate for elective and emergency surgeries under general anesthesia Consent to participate in the study

Exclusion criteria

Exclusion criteria: Having a history of severe cardiovascular disease Having a history of arrhythmia Having a history of taking blood pressure lowering drugs

Design outcomes

Primary

Measure	Time frame
Blood pressure. Timepoint: in basic times (before induction of anesthesia, anesthesia, before tracheal tube removal) and 1, 3, 5, and 10 minutes after tracheal tube removal. Method of measurement: Monitoring device.;Heart beat. Timepoint: in basic times (before induction of anesthesia, anesthesia, before tracheal tube removal) and 1, 3, 5, and 10 minutes after tracheal tube removal. Method of measurement: Monitoring device.	—

Measure

Time frame

Blood pressure. Timepoint: in basic times (before induction of anesthesia, anesthesia, before tracheal tube removal) and 1, 3, 5, and 10 minutes after tracheal tube removal. Method of measurement: Monitoring device.;Heart beat. Timepoint: in basic times (before induction of anesthesia, anesthesia, before tracheal tube removal) and 1, 3, 5, and 10 minutes after tracheal tube removal. Method of measurement: Monitoring device.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactBehzad Nazemroaya

Esfahan University of Medical Sciences

behzad_nazem@med.mui.ac.ir+98 31 3620 2020

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026