The effect of intravenous injection of pethidine and dexmedetomidine to prevent shivering after cesarean section under spinal anesthesia

Comparative study of intravenous injection of pethidine and dexmedetomidine to prevent shivering after cesarean section under spinal anesthesia

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200825048515N5

Enrollment

Registered

2020-10-05

Start date

2020-10-22

Completion date

Unknown

Last updated

2020-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Shivering after cesarean section. Hypothermia, not associated with low environmental temperature

Interventions

Intervention 1: Control group: For patients, spinal anesthesia in the lateral decubitus position and at the L3 and L4 levels in the midline is performed after the umbilical cord clamp. The patients ar

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Pregnancy Elective cesarean section with ASA score 1 and 2 Not addicted to drugs and alcohol based on the patient's statement

Exclusion criteria

Exclusion criteria: Previous use of painkillers, drugs and alcohol History of severe cardiovascular disease History of kidney and liver diseases Presence of drug allergy Seizures Having fever

Design outcomes

Primary

Measure	Time frame
Central temperature. Timepoint: Every 10 minutes during the operation until leaving the recovery unit. Method of measurement: Tympanic thermometer.;Peripheral temperature. Timepoint: Every 10 minutes during the operation until leaving the recovery unit. Method of measurement: Axillary thermometer.;Intensity of shivering. Timepoint: Every 10 minutes during the operation until leaving the recovery unit. Method of measurement: Based on five scores from 0 to 4 so that 0 = no shivering; 1= piloerection or peripheral vasoconstriction but no visible shivering; 2= muscular activity in only one muscle group; 3= muscular activity in more than one muscle group but not generalised shivering; 4= shivering involving the whole body.	—

Measure

Time frame

Central temperature. Timepoint: Every 10 minutes during the operation until leaving the recovery unit. Method of measurement: Tympanic thermometer.;Peripheral temperature. Timepoint: Every 10 minutes during the operation until leaving the recovery unit. Method of measurement: Axillary thermometer.;Intensity of shivering. Timepoint: Every 10 minutes during the operation until leaving the recovery unit. Method of measurement: Based on five scores from 0 to 4 so that 0 = no shivering; 1= piloerection or peripheral vasoconstriction but no visible shivering; 2= muscular activity in only one muscle group; 3= muscular activity in more than one muscle group but not generalised shivering; 4= shivering involving the whole body.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactBehzad Nazemroaya

Esfahan University of Medical Sciences

behzad_nazem@med.mui.ac.ir+98 31 3620 2020

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026