The effect of different doses of labetalol on bleeding volume during and after dacryocystorhinostomy surgery

The evaluation of the effect of different doses of labetalol on bleeding volume during and after dacryocystorhinostomy surgery

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200825048515N43

Enrollment

Registered

2021-10-02

Start date

2021-10-23

Completion date

Unknown

Last updated

2021-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dacryocystorhinostomy. Dacryoadenitis

Interventions

Intervention 1: First intervention group: In this group, labetalol at a dose of 0.2 mg / kg will be administered as an infusion 5 minutes after induction of anesthesia. Intervention 2: The second inte

Eligibility

Sex/Gender

All

Age

20 Years to 64 Years

Inclusion criteria

Inclusion criteria: Candidate for elective dacryocystorhinostomy surgery Age range 20 to 64 years Class I and II classification of the American Society of Anesthesiologists

Exclusion criteria

Exclusion criteria: History of blood diseases, coagulopathy Allergy to labetalol Existence of any uncontrolled systemic disease Recent use of anticoagulants History of malignant hyperthermia

Design outcomes

Primary

Measure	Time frame
Bleeding volume. Timepoint: During surgery and in recovery. Method of measurement: Measure the amount of blood in the suction.	—

Secondary

Measure	Time frame
Systolic blood pressure. Timepoint: Immediately before surgery and then every 15 minutes during surgery and then every 15 minutes to an hour in recovery. Method of measurement: Monitoring device.;Diastolic blood pressure. Timepoint: Immediately before surgery and then every 15 minutes during surgery and then every 15 minutes to an hour in recovery. Method of measurement: Monitoring device.;Mean Arterial Pressure. Timepoint: Immediately before surgery and then every 15 minutes during surgery and then every 15 minutes to an hour in recovery. Method of measurement: Monitoring device.;Hear rate. Timepoint: Immediately before surgery and then every 15 minutes during surgery and then every 15 minutes to an hour in recovery. Method of measurement: Monitoring device.	—

Measure

Time frame

Systolic blood pressure. Timepoint: Immediately before surgery and then every 15 minutes during surgery and then every 15 minutes to an hour in recovery. Method of measurement: Monitoring device.;Diastolic blood pressure. Timepoint: Immediately before surgery and then every 15 minutes during surgery and then every 15 minutes to an hour in recovery. Method of measurement: Monitoring device.;Mean Arterial Pressure. Timepoint: Immediately before surgery and then every 15 minutes during surgery and then every 15 minutes to an hour in recovery. Method of measurement: Monitoring device.;Hear rate. Timepoint: Immediately before surgery and then every 15 minutes during surgery and then every 15 minutes to an hour in recovery. Method of measurement: Monitoring device.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactDaroush Moradi Farsani

Esfahan University of Medical Sciences

dmoradi@med.mui.ac.ir+98 31 3445 2034

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026