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Evaluation of the effect of extracorporeal shockwave therapy after botulinum toxin injection on cuff muscle spasticity improvement

Evaluation of the effect of extracorporeal shockwave therapy after botulinum toxin injection on cuff muscle spasticity improvement in patients with multiple sclerosis

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200825048515N41
Enrollment
20
Registered
2021-09-27
Start date
2021-09-23
Completion date
Unknown
Last updated
2021-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multiple sclerosis. Multiple sclerosis

Interventions

Intervention 1: Control group: In this group, only botulinum toxin injection with BTX-A was performed for the patient under the standard protocol, for this purpose, 100-200 mU of Botox type A, Dysport

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Definitive diagnosis of multiple sclerosis based on the opinion of a neurologist Presence of spasticity in the cuff muscles (based on a score of more than 1 on the modified Ashworth scale (MAS) consent to participate in the study

Exclusion criteria

Exclusion criteria: Having cognitive disorders (in advanced stages of the disease) Having myopathy or peripheral nerve disease Having a pace maker Pregnancy Pre-injection of botulinum toxin during the last 6 months Having cuff muscle atrophy Having coagulation disorders History of previous surgery or fracture at the site of spastic muscles

Design outcomes

Primary

MeasureTime frame
Pain. Timepoint: Before, immediately, 2 weeks and 8 weeks after the intervention. Method of measurement: Visual Analogue Scale (VAS).;Spasticity score. Timepoint: Before, immediately, 2 weeks, and 8 weeks after the intervention. Method of measurement: Modified Ashworth's Scale (MAS).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactShila Haghighat

Esfahan University of Medical Sciences

Haghighatshila@gmail.com+98 31 3620 2020

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026