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Comparison of the effect of ketorolac and morphine on pain control in patients with renal colic

A comparative study of the effect of intravenous ketorolac and morphine on pain control in patients with renal colic

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200825048515N40
Enrollment
272
Registered
2021-09-26
Start date
2019-10-23
Completion date
Unknown
Last updated
2021-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Renal colic. Unspecified renal colic

Interventions

Intervention 1: First intervention group: For patients in this group, morphine (Iran Darou Pharmaceutical Company) is administered intravenously at a dose of 1 mg/kg. Intervention 2: Second interventi

Sponsors

Shahre-kord University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
16 Years to 65 Years

Inclusion criteria

Inclusion criteria: age range of 16-65 years The definitive diagnosis of renal colic (with renal colic symptoms and the presence of stones confirmed by CT) The weight of 50-100 kg (for the effectiveness of the dose of 30 mg ketorolac) The pain intensity of equal to or more than 7 The non-drug addiction The patients’ consent to participate in the study

Exclusion criteria

Exclusion criteria: Having a history of morphine or ketorolac allergy Pregnancy or suspected pregnancy Breastfeeding Having history of taking painkillers over the last 4 hours Having a history of underlying diseases Having traumatic eye or head injuries Having one kidney or a kidney transplant Having cerebral hemorrhage or the possibility of its occurrence Having mental disorders Having fibromyalgia Having vascular and brain lesions Having coagulation disorders, using angiotensin-converting enzyme (ACE) inhibitor or anticoagulants

Design outcomes

Primary

MeasureTime frame
Pain score. Timepoint: At the beginning of the study and at 5, 15, 30, 60 and 90 minutes after the intervention. Method of measurement: Visual Analogue Scale (VAS).

Secondary

MeasureTime frame
Mean Arterial Pressure. Timepoint: At the beginning of the study and at 5, 15, 30, 60 and 90 minutes after the intervention. Method of measurement: Monitoring device.;Hear rate. Timepoint: At the beginning of the study and at 5, 15, 30, 60 and 90 minutes after the intervention. Method of measurement: Monitoring device.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyed Mehdi Pourafzali

Esfahan University of Medical Sciences

e.poursadra@gmail.com+98 38 3333 0061

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026