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The effect of topical injection of "morphine, triamcinolone and lidocaine" and "lidocaine alone" on postoperative pain intensity

Evaluation of the effect of topical injection of "morphine, triamcinolone and lidocaine" in comparison with "lidocaine" on pain intensity after mastoidectomy-tympanoplasty

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200825048515N39
Enrollment
68
Registered
2021-09-20
Start date
2021-09-23
Completion date
Unknown
Last updated
2021-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mastoidectomy-tympanoplasty Surgery.

Interventions

Intervention 1: Intervention group: In this group, 0.15 mg/kg morphine (Daru Pakhsh Company) and 10 mg triamcinolone (Germany Hexal Company) to 100 mg lidocaine 2% (Aburaihan Tehran) and epinephrine w

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 65 Years

Inclusion criteria

Inclusion criteria: Age 15 to 65 years Indicated for mastoidectomy-tympanoplasty Satisfaction to participate in the study

Exclusion criteria

Exclusion criteria: Having a history of drug and alcohol addiction Having a history of seizures and mental health problems Having kidney disease Death of the patient

Design outcomes

Primary

MeasureTime frame
Pain score. Timepoint: Immediately upon entering the recovery and at 2, 8, 12 and 24 hours after surgery. Method of measurement: Visual Analogue Scale.

Secondary

MeasureTime frame
Systolic blood pressure. Timepoint: Before induction of anesthesia, immediately after induction of anesthesia and every ten minutes during surgery until the end of surgery. Method of measurement: Monitoring device.;Diastolic blood pressure. Timepoint: Before induction of anesthesia, immediately after induction of anesthesia and every ten minutes during surgery until the end of surgery. Method of measurement: Monitoring device.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactReihanak Talakoub

Esfahan University of Medical Sciences

Talakoub@med.mui.ac.ir+98 31 3620 2020

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 8, 2026