The effectiveness of epinephrine spray on papillae for prevention of pancreatitis

Evaluation the effectiveness of epinephrine spray on papillae in prevention of post-Endoscopic retrograde cholangiopancreatography(ERCP) pancreatitis

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200825048515N35

Enrollment

164

Registered

2021-06-11

Start date

2021-06-20

Completion date

Unknown

Last updated

2021-06-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Biliary pancreatitis. Biliary acute pancreatitis

Interventions

Intervention 1: Control group: Patients in this group receive 50 mg indomethacin suppository, before the ERCP. In addition, during ERCP and before cannulation, the normal saline is sprayed locally on

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age 18 years or older Having an intact papillae No deformity ? Papilla Consent to participate in the study

Exclusion criteria

Exclusion criteria: Having acute pancreatitis Having chronic pancreatitis with an acute exacerbation Above normal serum amylase level or lipase level (> 200 units per liter) Having bile duct cancer Previous ERCP history or papilla manipulation Allergy to epinephrine

Design outcomes

Primary

Measure	Time frame
Frequency of cannulation. Timepoint: 24 hours after ERCP operation. Method of measurement: Observation.;Incidence of pancreatitis. Timepoint: 24 hours after ERCP operation. Method of measurement: Examination and testing of amylase lipase.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Karami

Shahre-kord University of Medical Sciences

Bahman_salem@yahoo.com+98 38 3333 0061

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026