Evaluation of preventive effect of injection paracetamol and lidocaine in reducing pain caused by intravenous injection of propofol in children

Evaluation of preventive effect of injection paracetamol and lidocaine in reducing pain caused by intravenous injection of propofol in children aged 4 to 6 years

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200825048515N34

Enrollment

Registered

2021-05-30

Start date

2021-06-05

Completion date

Unknown

Last updated

2021-06-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Inguinal surgery. Inguinal hernia

Interventions

Intervention 1: Intervention group 1: Patients in this group are injected with 1 mg / kg intravenous paracetamol one minute before propofol administration. Intervention 2: Intervention group 2: Patien

Eligibility

Sex/Gender

All

Age

4 Years to 6 Years

Inclusion criteria

Inclusion criteria: Children 4-6 years Has the American Association of Anesthesiologists (ASA) One and Two Candidate for inguinal surgery under general anesthesia with propofol

Exclusion criteria

Exclusion criteria: Has underlying diseases (including liver, cardiovascular, neurological, metabolic disease, dermatitis) Having drug allergies

Design outcomes

Primary

Measure	Time frame
Pain score. Timepoint: During injection of propofol. Method of measurement: Behavioral scale derived from the Face, Leg, Activity, Cry, Consolability (FLACC).;Agitation score. Timepoint: During injection of propofol. Method of measurement: According to Richmond criteria.;Mean Arterial Pressure. Timepoint: Before and one minute after the intervention. Method of measurement: Monitoring device.;Hear rate. Timepoint: Before and one minute after the intervention. Method of measurement: Monitoring device.	—

Measure

Time frame

Pain score. Timepoint: During injection of propofol. Method of measurement: Behavioral scale derived from the Face, Leg, Activity, Cry, Consolability (FLACC).;Agitation score. Timepoint: During injection of propofol. Method of measurement: According to Richmond criteria.;Mean Arterial Pressure. Timepoint: Before and one minute after the intervention. Method of measurement: Monitoring device.;Hear rate. Timepoint: Before and one minute after the intervention. Method of measurement: Monitoring device.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactSedigheh Shah-Hosseini

Esfahan University of Medical Sciences

nasrin90ir@gmail.com+98 31 3620 2020

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026