Effect of atropine administration before induction of anesthesia on the incidence of delirium and complications in post-anesthesia care unit among children aged 1-6 years old undergoing lower abdominal surgery as compared with the control group

Evaluation of effect of atropine administration before induction of anesthesia on the incidence of delirium and complications in post-anesthesia care unit among children aged 1-6 years old undergoing lower abdominal surgery as compared with the control group

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200825048515N33

Enrollment

Registered

2021-05-13

Start date

2021-05-22

Completion date

Unknown

Last updated

2021-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lower abdomen surgery.

Interventions

Intervention 1: Intervention group 1: patients in this group receive 0.02 mg/kg of atropine before induction of anesthesia (after dilution with a volume of 0.1 mg per cc). Intervention 2: Control grou

Eligibility

Sex/Gender

All

Age

1 Years to 6 Years

Inclusion criteria

Inclusion criteria: Age category 1 to 6 years old Candidate for lower abdominal surgery Class I and II classification of the American Society of Anesthesiologists Parents' consent to participate in the study

Exclusion criteria

Exclusion criteria: Having a child with a psychiatric problem, including ADHD and depression and other behavioral disorders

Design outcomes

Primary

Measure	Time frame
Delirium score. Timepoint: Immediately upon entering the recovery ward and 15, 30 and 45 minutes later in the recovery. Method of measurement: Pediatric Anesthesia Emergence Delirium Scale (PAED).;Pain score. Timepoint: 15, 30 and 45 minutes later in the recovery. Method of measurement: Behavioral scale derived from the Face, Leg, Activity, Cry, Consolability (FLACC).;Blood Pressure. Timepoint: Immediately after surgery, in the minutes of 15, 30, and 45 during surgery and immediately, 15, 30, and 45 minutes after recovery. Method of measurement: Monitoring device.;Heart rate. Timepoint: Immediately after surgery, in the minutes of 15, 30, and 45 during surgery and immediately, 15, 30, and 45 minutes after recovery. Method of measurement: Monitoring device.;Percentage of oxygen saturation. Timepoint: Immediately after surgery, in the minutes of 15, 30, and 45 during surgery and immediately, 15, 30, and 45 minutes after recovery. Method of measurement: Monitoring device.	—

Measure

Time frame

Delirium score. Timepoint: Immediately upon entering the recovery ward and 15, 30 and 45 minutes later in the recovery. Method of measurement: Pediatric Anesthesia Emergence Delirium Scale (PAED).;Pain score. Timepoint: 15, 30 and 45 minutes later in the recovery. Method of measurement: Behavioral scale derived from the Face, Leg, Activity, Cry, Consolability (FLACC).;Blood Pressure. Timepoint: Immediately after surgery, in the minutes of 15, 30, and 45 during surgery and immediately, 15, 30, and 45 minutes after recovery. Method of measurement: Monitoring device.;Heart rate. Timepoint: Immediately after surgery, in the minutes of 15, 30, and 45 during surgery and immediately, 15, 30, and 45 minutes after recovery. Method of measurement: Monitoring device.;Percentage of oxygen saturation. Timepoint: Immediately after surgery, in the minutes of 15, 30, and 45 during surgery and immediately, 15, 30, and 45 minutes after recovery. Method of measurement: Monitoring device.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmir Shafa

Esfahan University of Medical Sciences

shafa_amir@yahoo.com+98 31 3620 2020

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026