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Comparison of ovarian reserve in laparoscopic endometrioma surgery with and without vasopressin injection

Comparison of ovarian reserve in laparoscopic endometrioma surgery with and without vasopressin injection

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200825048515N26
Enrollment
44
Registered
2021-03-30
Start date
2021-03-21
Completion date
Unknown
Last updated
2021-04-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ovarian endometrioma. Endometriosis of ovary

Interventions

Intervention 1: Intervention group: In this group, 20 units of diluted vasopressin (Elixir Pharmaceutical Company) will be diluted by 200 times (0.1 units per ml) during surgery. 3 ml of diluted vasop

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Diagnosis of unilateral ovarian endometrioma by ultrasound The size of the cyst should be between 30 and 70 mm Lack of the evidence of ovarian cancer Normal menstrual cycle Individuals with symptomatic endometrioma and surgical indications (infertility, failed assistedreproductive technology (ART) treatment cycles, pelvic pain)

Exclusion criteria

Exclusion criteria: Patient’s pregnancy Body mass index above 30 kg/m² History of any malignancy Detection of ovarian cysts other than endometrioma after surgery Atypical endometrioma History of kidney, liver, and heart diseases (hypertension - cardiac arrhythmia - ischemia) Use of combined contraceptive pills before surgery (over the last three months) Previous surgery of endometrioma Polycystic ovary syndrome

Design outcomes

Primary

MeasureTime frame
Number of antral ovarian follicles. Timepoint: Before and three months after surgery. Method of measurement: Transvaginal ultrasound.;Serum levels of anti mullerian hormone. Timepoint: Before and three months after surgery. Method of measurement: Kit made by Biomeriux company.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSafoura Rouholamin

Esfahan University of Medical Sciences

s_rouholamin@med.mui.ac.ir+98 31 3620 2020

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026