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The effect of topical betamethasone and oral melatonin in the treatment of atopic dermatitis

Comparison of the effect of topical betamethasone with oral melatonin in the treatment of atopic dermatitis

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200825048515N23
Enrollment
50
Registered
2021-02-14
Start date
2021-02-18
Completion date
Unknown
Last updated
2021-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atopic dermatitis. Atopic dermatitis, unspecified

Interventions

Intervention 1: Control group: In this group, patients receive topical betamethasone and an emollient twice a day. They have also prescribed a placebo tablet (which looks similar to melatonin) at bedt

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Age between 18-65 years Satisfaction to participate in the study

Exclusion criteria

Exclusion criteria: Extent of involvement less than 2% or more than 30% of the body surface Skin problems other than atopic dermatitis Severe systemic diseases (kidney disease, diabetes, uncontrolled hypertension, and other chronic diseases) Use of systemic medications for atopic dermatitis 4 weeks before the start of the study Use of topical medications for atopic dermatitis 2 weeks before the start of the study

Design outcomes

Primary

MeasureTime frame
Scaling severity. Timepoint: 4, 8 and 12 weeks and 3 months after intervention. Method of measurement: Scoring Index for Atopic Dermatitis (SCORAD).;Blister severity. Timepoint: 4, 8 and 12 weeks and 3 months after intervention. Method of measurement: Scoring Index for Atopic Dermatitis (SCORAD).;Redness severity. Timepoint: 4, 8 and 12 weeks and 3 months after intervention. Method of measurement: Scoring Index for Atopic Dermatitis (SCORAD).;Dermatitis severity. Timepoint: 4, 8 and 12 weeks and 3 months after intervention. Method of measurement: Scoring Index for Atopic Dermatitis (SCORAD).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFariba Iraji

Esfahan University of Medical Sciences

iraji@med.mui.ac.ir+98 31 3620 2020

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026