The effect of fentanyl and sufentanil in combination with propofol on changes in heart rate and blood pressure after laryngoscopy and endotracheal intubation

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200825048515N18

Enrollment

Registered

2021-01-01

Start date

2020-11-21

Completion date

Unknown

Last updated

2021-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients under general anesthesia require endotracheal intubation.

Interventions

Intervention 1: Control group: In this group for patients, induction of anesthesia with normal saline at the time of induction of anesthesia with lidocaine 1.5 mg/kg, propofol 2 mg/kg with atracurium

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Age range between 18-65 years, American Society of Anesthesiologists (ASA) classification equal to I or II General anesthesia candidates require endotracheal intubation

Exclusion criteria

Exclusion criteria: Having kidney, liver, heart, or lung failure Addiction Having an airway abnormality Being allergic to the drugs under study

Design outcomes

Primary

Measure	Time frame
Heart beat. Timepoint: Immediately before, 1, 3, 5 and 10 minutes after laryngoscopy. Method of measurement: Monitoring device.;Blood pressure. Timepoint: Immediately before, 1, 3, 5 and 10 minutes after laryngoscopy. Method of measurement: Monitoring device.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAzim Honarmand

Esfahan University of Medical Sciences

honarmand@med.mui.a.ir+98 31 3620 2020

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026