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Effect of Magnesium Sulfate on the control of bleeding during Lumbar Spinal Fusion Surgery

Comparing the Effect of Two Injections Doses of Magnesium Sulfate (40 and 50 mg) on the Control of Bleeding during Lumbar Spinal Fusion Surgery

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200825048515N15
Enrollment
60
Registered
2020-12-10
Start date
2020-12-21
Completion date
Unknown
Last updated
2021-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lumbar Spinal Fusion Surgery. Fusion of spine, lumbar region

Interventions

Intervention 1: Control group: After preparing patents for intravenous injection and administration of 500 cc of normal saline before induction of anesthesia, all patients will be pre-oxygenated with
The first group, as a control group, will receive only normal saline intravenously within 10 minutes. Intervention 2: Intervention group: Patients in this group, in addition to induction of anesthesia

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients who are candidates for lumbar spinal fusion surgery Aged between 20 and 60 years ASA I and II based on America Society of Anesthesiologists (ASA) classification Being consent to participate in the study

Exclusion criteria

Exclusion criteria: Allergy to magnesium sulfate Liver, kidney, cardiovascular failure Opioid use Consumption of NSAIDs Consumption of calcium channel blockers

Design outcomes

Primary

MeasureTime frame
Systolic blood pressure. Timepoint: Before surgery, immediately after surgery and 15, 30, 45, and 60 minutes during surgery and in recovery. Method of measurement: Monitoring device.;Diastolic blood pressure. Timepoint: Before surgery, immediately after surgery and 15, 30, 45 and 60 minutes during surgery and in recovery. Method of measurement: Monitoring device.;Hear rate. Timepoint: Before surgery, immediately after surgery and 15, 30, 45 and 60 minutes during surgery and in recovery. Method of measurement: Monitoring device.;Amount of bleeding. Timepoint: During surgery and in recovery. Method of measurement: Blood in suction and gauze.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZahra Rahimi

Esfahan University of Medical Sciences

dr.zahrarahimi@yahoo.com+98 31 3620 2020

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026