The Effect of Vitamin D Supplementation on Improvement of Symptoms in Asthma Patients with Vitamin D Insufficiency and Deficiency

The Effect of Vitamin D Supplementation on Improvement of Symptoms in Mild-to-Moderate Asthma Patients with Vitamin D Insufficiency and Deficiency

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200825048515N10

Enrollment

132

Registered

2020-10-24

Start date

2015-08-23

Completion date

Unknown

Last updated

2020-11-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Asthma. Asthma

Interventions

Intervention 1: Control group: Patients with asthma and vitamin D deficiency, in addition to receiving conventional asthma control medications (SymbiCort inhalation spray), received placebo for 6 week

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with mild-to-moderate asthma Patients with vitamin D insufficiency and deficiency Being consent to participate in the study

Exclusion criteria

Exclusion criteria: Diagnosis of chronic obstructive pulmonary disease (COPD) Sarcoidosis Hyperthyroidism Kidney stones Active tuberculosis Vitamin D intolerance Liver failure Kidney failure Suffering from lymphomas or other malignant tumors that have not healed in more than two years of treatment Treatment with anticonvulsant drugs, vitamin D supplements Treatment with systemic corticosteroids for more than 3 months prior to study Breastfeeding or pregnancy a basal serum calcium concentration of >2.65 mmol / L Exacerbation of asthma in the three months before the study Active or inactive smoking

Design outcomes

Primary

Measure	Time frame
Control of asthma symptoms. Timepoint: Before the intervention and three months after the intervention. Method of measurement: Asthma Control Test (ACT score).;FEV1 parameter. Timepoint: Before the intervention and three months after the intervention. Method of measurement: Spirometer device.;FVCparameter. Timepoint: Before the intervention and three months after the intervention. Method of measurement: Spirometer device.;Serum vitamin D level. Timepoint: Before the intervention and three months after the intervention. Method of measurement: Radioimmunoassay method.	—

Measure

Time frame

Control of asthma symptoms. Timepoint: Before the intervention and three months after the intervention. Method of measurement: Asthma Control Test (ACT score).;FEV1 parameter. Timepoint: Before the intervention and three months after the intervention. Method of measurement: Spirometer device.;FVCparameter. Timepoint: Before the intervention and three months after the intervention. Method of measurement: Spirometer device.;Serum vitamin D level. Timepoint: Before the intervention and three months after the intervention. Method of measurement: Radioimmunoassay method.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Emami Ardestani

Esfahan University of Medical Sciences

m_emamiardestani@med.mui.ac.ir+98 31 3620 2020

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026