Patients undergoing open heart surgery.
Conditions
Interventions
Intervention 1: Intervention group for patients taking 1200 mg of NAC once in prime during cardiopulmonary pumping 1200 mg of NAC. Intervention 2: Control group: For patients who are not taking NAC.
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
40 Years to 65 Years
Inclusion criteria
Inclusion criteria: Age 40 to 65 years GFR greater than 60 Creatinine less than 1.5 Having conscious satisfaction Patients with no previous history of open heart surgery Patients undergoing CABG coronary artery bypass graft surgery Patients who did not use ECMO and pump balloons before open heart surgery
Exclusion criteria
Exclusion criteria: Patients undergoing CABG without Cardiopulmonary pump (CPB) Patients who had valve surgery in addition to CABG surgery Patients who are candidates for emergency CABG
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluation of BUN. Timepoint: One and two days after surgery. Method of measurement: Through blood tests and sheets available in the ICU.;Creatinine. Timepoint: One and two days after surgery. Method of measurement: Through blood tests and sheets available in the ICU.;Urinary output. Timepoint: One and two days after surgery. Method of measurement: Through blood tests and sheets available in the ICU. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactLeila Roustazadeh Sheikh Yousefi
Esfahan University of Medical Sciences
Outcome results
None listed