lithorex-B in ureteral stones

Efficacy of Lithorex-B versus Tamsulosin in medical expulsive therapy of ureteral stones in adults

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200822048478N1

Enrollment

102

Registered

2020-09-07

Start date

2020-09-10

Completion date

Unknown

Last updated

2020-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ureteral stone. Calculus of ureter

Interventions

Intervention 1: First intervention group: Group receiving Litorex-B 400mg tablet (Barij Essence Pharmaceutical Company) every 6 hours with analgesic (diclofenac sodium 25mg, Hakim Pharmaceutical Compa

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: ureteral stone diameter less than 10 mm age over 18

Exclusion criteria

Exclusion criteria: Pregnancy and lactation Taking drugs that affect kidney stones azotemia active UTI severe cardiovascular or respiratory disease The need for immediate intervention to remove the stone surgical treatment candidate taking diuretic drugs taking calcium gastrointestinal bleeding hypersensitivity reaction Itching, skin rash and contact dermatitis History of allergy to salicylates Coagulopathy Nasal polyps and asthma

Design outcomes

Primary

Measure	Time frame
Frequency of stone excretion. Timepoint: The duration of the study is 4 weeks. Individuals will be followed up weekly during the study period. Follow-up of patients at the beginning and end of the study will be clinical and at the end of the first, second and third weeks by telephone. Method of measurement: Use of a checklist that includes: clinical examination, interview with the patient and the result of ultrasound.;Stone diameter. Timepoint: The duration of the study is 4 weeks. Individuals will be followed up weekly during the study period. Follow-up of patients at the beginning and end of the study will be clinical and at the end of the first, second and third weeks by telephone. Method of measurement: Use of a checklist that includes: clinical examination, interview with the patient and the result of ultrasound.	—

Measure

Time frame

Frequency of stone excretion. Timepoint: The duration of the study is 4 weeks. Individuals will be followed up weekly during the study period. Follow-up of patients at the beginning and end of the study will be clinical and at the end of the first, second and third weeks by telephone. Method of measurement: Use of a checklist that includes: clinical examination, interview with the patient and the result of ultrasound.;Stone diameter. Timepoint: The duration of the study is 4 weeks. Individuals will be followed up weekly during the study period. Follow-up of patients at the beginning and end of the study will be clinical and at the end of the first, second and third weeks by telephone. Method of measurement: Use of a checklist that includes: clinical examination, interview with the patient and the result of ultrasound.

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Secondary

Measure	Time frame
Possible side effects. Timepoint: The duration of the study is 4 weeks. Individuals will be followed up weekly during the study period. Follow-up of patients at the beginning and end of the study will be clinical and at the end of the first, second and third weeks by telephone. Method of measurement: Use of a checklist that includes: clinical examination, interview with the patient and the result of ultrasound.;Pain. Timepoint: The duration of the study is 4 weeks. Individuals will be followed up weekly during the study period. Follow-up of patients at the beginning and end of the study will be clinical and at the end of the first, second and third weeks by telephone. Method of measurement: Use of a checklist that includes: clinical examination, interview with the patient and the result of ultrasound.	—

Measure

Time frame

Possible side effects. Timepoint: The duration of the study is 4 weeks. Individuals will be followed up weekly during the study period. Follow-up of patients at the beginning and end of the study will be clinical and at the end of the first, second and third weeks by telephone. Method of measurement: Use of a checklist that includes: clinical examination, interview with the patient and the result of ultrasound.;Pain. Timepoint: The duration of the study is 4 weeks. Individuals will be followed up weekly during the study period. Follow-up of patients at the beginning and end of the study will be clinical and at the end of the first, second and third weeks by telephone. Method of measurement: Use of a checklist that includes: clinical examination, interview with the patient and the result of ultrasound.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactHosein Akbari

Kashan University of Medical Sciences

akbari1350_h@yahoo.com+98 31 5554 0021

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026